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The Pathogenetic Mechanism of Optic Atrophy

The optic nerve is a tube that runs from the retina to the cerebral cortex, carrying video signals. As the optic nerve is affected, it loses the ability to send messages to the brain. Optic nerve disorders, such as optic neuropathy (optic nerve atrophy), are progressive and degenerative pathologies of the optic nerve that invariably result in vision failure. Apoptosis (programmed death) in retinal nerve cells or other nearby nerve tissues causes the majority of optic nerve disorders. Pathophysiological processes of occurrence are diverse in certain pathologies. Their incidence may be caused by a variety of factors: Glaucoma (higher intraocular pressure), myopia, retinitis pigmentosa, eye infections, pathological processes, retinal damage, optic nerve irritation (neuritis), and other ophthalmic disorders. Injuries include craniocerebral damage and trauma to the eye's systems. Meningioma, osteosarcoma, optic nerve glioma, and orbital malignant tumours are also examples of neo